Who needs anti-viral drugs in swine flu?
Facts Published by IMA – Indian Medical Association
- In the United States, 0.3% of all cases require admissions.
- The mortality rate of flu pandemic is 0.12 deaths per 100,000 population.
- Total number of deaths caused by pandemic H1N1 influenza A in the United States was lower than the number of deaths caused by seasonal influenza during non-pandemic years
- Early and prompt initiation of antiviral therapy is recommended for children, adolescents, or adults with suspected or confirmed swine flu with any of the following features:
- Flu requiring hospitalization
- Progressive, severe, or complicated flu
- Severely immunosuppressed patients (receiving treatment for malignancies, hematopoietic or solid organ transplant recipients)
- Swine flu at high risk for complications:
- Children <5 years particularly those <2 years
- Elderly =65 years
- Pregnant women
- Women up to 2 weeks postpartum
- Residents of nursing homes and other chronic care facilities
- Individuals with chronic medical conditions including: lung disease, including asthma (particularly if steroids have been required during the past year); heart disease, except isolated hypertension; active malignancy; chronic kidney disease, chronic liver disease, diabetes, sickle cell disease, other chronic disabling diseases and morbid obesity.
- Severity of flu
- Asymptomatic swine flu: Many contact illnesses may pass off without symptoms. In all 19 percent had serologically confirmed infection and 28 percent of those who were infected may remain asymptomatic.
- Mild or uncomplicated swine flu (require no treatment, no hospitalization, no investigations)
- Fever, cough, sore throat, nasal discharge, muscle pain, headache, chills, malaise and sometimes diarrhea and vomiting
- No shortness of breath
- Little change in chronic health conditions.
- Progressive illness. Requires hospitalization
- Above symptoms plus
- Chest pain
- Poor oxygenation (high respiratory rate, hypoxia, labored breathing in children)
- Low blood pressure
- Confusion, altered mental status
- Severe dehydration
- Exacerbations of asthma, chronic bronchitis, chronic renal failure, diabetes, or other cardiovascular conditions
- Severe or complicated illness requires hospitalization
- Signs of lower respiratory tract disease
- Low oxygen requiring supplemental oxygen
- Pneumonia on x-ray
- Brain involvement
- BP lower than 80, organ failure
- Heart involvement
- Persistent high fever and other symptoms beyond 3 days
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