Professor Khuda-Bukhsh and Homoeopathy

September 17, 2015 admin Research in Homoeopathy 3

Bukhsh KhudaProfessor Anisur Rahman Khuda-Bukhsh PhD., is a professor at the Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani-741235, India.

He has conducted groundbreaking investigations on homeopathic medicine. Khuda-Bukhsh  is somewhat like a research centre.  He has published nearly 15o  scientific articles in peer-reviewed  medical journals related to homeopathy but many homeopaths  have  never  heard  of  him.

He  was  a scientist  who  had thoroughly understood the theoretical principles of homeopathy. He was not only clear about the key questions, but also had the ability to communicate his understanding with clarity and the necessary detail.

Some of the relevant and prominent publications on homeopathy in International/National journals.

  1. Ghosh S, Sikdar S, Mukherjee A, Khuda-Bukhsh AR. Evaluation of chemopreventive potentials of ethanolic extract of Ruta graveolens against A375 skin melanoma cells in vitro and induced skin cancer in mice in vivo. J Integr Med. 2015 Jan;13(1):34-44. doi: 10.1016/S2095-4964(15)60156-X.
  2. Khuda-Bukhsh AR. Current trends in ultra-high dilution research with particular reference to gene regulatory hypothesis: Review article. The Nucleus (Springer) Nucleus DOI 10.1007/s13237-014-0105-0,
  3. Mondal J, Panigrahi AK,Khuda-Bukhsh AR. Anticancer potential of Conium maculatum extract against cancer cells in vitro: Drug-DNA interaction and its ability to induce apoptosis through ROS generation. Pharmacogn Mag. 2014 Aug;10(Suppl 3):S524-33. doi: 10.4103/0973-1296.139792.
  4. Mondal J, Bishayee K, Panigrahi AK,Khuda-Bukhsh  Low doses of ethanolic extract of Boldo (Peumus boldus) can ameliorate toxicity generated by cisplatin in normal liver cells of mice in vivo and in WRL-68 cells in vitro, but not in cancer cells in vivo or in vitro. J Integr Med. 2014 Sep;12(5):425-38. doi: 10.1016/S2095-4964(14)60045-5.
  5. Sikdar, S, Mukherjee A, Khuda-Bukhsh AR. Ethanolic Extract of Marsdenia condurango ameliorates Benzo[a]pyrene-induced lung cancer of rats. Journal of Pharmacopuncture, 2014, Vol. 17: (p7-17).
  6. Sikdar S and Khuda-Bukhsh AR. Condurango 30C induces epigenetic modification of lung cancer specific tumour suppressor genes via demethylation. Forschende Komplementarmetizin/Research in Complementary Medicine. (In Press).
  7. Saha S and Khuda-Bukhsh AR. Berberine alters epigenetic modifications, disrupts microtubule network, and modulates HPV-18E6-E7 oncoproteins by targeting p53 in cervical cancer cell HeLa: A mechanistic study including molecular docking. European Journal of Pharmacology, 2014; 244:132-146.
  8. Mukherjee A, Sikdar S, Bishayee K, Boujedaini N, Khuda-Bukhsh AR. Flavonol isolated from ethanolic leaf extract of Thuja occidentalis arrests the cell cycle at G2-M and induces ROS-independent apoptosis in A549 cells, targeting nuclear DNA. Cell 2014;47:56-71. doi: 10.1111/cpr.12079.
  9. Sikdar S, Saha SK, Khuda-Bukhsh AR. Relative apoptosis-inducing potential of homeopathic Condurango 6C and 30C in H460 lung cancer cells in vitro: the signaling cascade. Journal of Pharmacopuncture, 2014, 17: (p59-69), 17.
  10. Sikdar S, Khuda-Bukhsh AR. Post-cancer treatment of Condurango 30C, traditionally used in homeopathy, ameliorates tissue damage and stimulates reactive oxygen species in benzo[a]pyrene-induced lung cancer of rat. Humanitas Traditional Medicine (TANG), 2013, 3, e25. http://www.ncbi.nlm.nih.gov/pubmed/23579292
  11. Sikdar S, Mukherjee A, Bishayee K, Paul A, Saha S, Ghosh S, Chakraborty D, Boujedaini N, Khuda-Bukhsh A.R. Assessment of apoptotic and anticancer potentials of a potentized homeopathic drug, Condurango 30C, in Benzo[a]pyrene-induced lung cancer of rat: the signalling cascade. Journal of Pharmacopuncture, 2013; 16:011-022.
  12. Saha SK, Roy S, Khuda-Bukhsh AR. Evidence in support of gene regulatory hypothesis: Gene expression profiling manifests homeopathy effect as more than placebo. Int J High Dilution Res 2013;12:162-7.
  13. Saha SK, Sikdar S, Mukherjee A, Bhadra K, Boujedaini N, Khuda-Bukhsh Ethanolic extract of the Goldenseal, Hydrastis canadensis, has demonstrable chemopreventive effects on HeLa cells in vitro: Drug-DNA interaction with calf thymus DNA as target. Environ Toxicol Pharmacol. 2013;36:202-14. doi: 10.1016/j.etap.2013.03.023.
  14. Sikdar S, Mukherjee A, Ghosh S, Khuda-Bukhsh AR. Condurango glycoside-rich components stimulate DNA damage-induced cell cycle arrest and ROS-mediated caspase-3 dependent apoptosis through inhibition of cell-proliferation in lung cancer, in vitro and in vivo. Environ Toxicol Pharmacol. 2013;37:300-314.
  15. Das S, Das J, Samadder A, Paul A, Khuda-Bukhsh AR. Efficacy of PLGA-loaded apigenin nanoparticles in Benzo[a]pyrene and ultraviolet-B induced skin cancer of mice: Mitochondria mediated apoptotic signalling cascades. Food Chem Toxicol. 2013 Oct 9. doi:pii: S0278-6915(13)00675-3. 10.1016/j.fct.2013.09.037.
  16. Das S, Das J, Samadder A, Paul A, Khuda-Bukhsh AR. Strategic formulation of apigenin-loaded PLGA nanoparticles for intracellular trafficking, DNA targeting and improved therapeutic effects in skin melanoma in vitro. Toxicol Lett. 2013 Sep 23. doi:pii: S0378-4274(13)01326-X. 10.1016/j.toxlet.2013.09.012
  17. Bishayee K, Paul A, Ghosh S, Sikdar S, Mukherjee A, Biswas R, Boujedaini N, Khuda-Bukhsh AR. Condurango-glycoside-A fraction of Gonolobus condurango induces DNA damage associated senescence and apoptosis via ROS-dependent p53 signalling pathway in HeLa cells. Mol Cell Biochem. 2013; 382:173-83.
  18. Bishayee K, Sikdar S, Khuda-Bukhsh AR. Ultra-HighlyDiluted Gonolobus Condurango Extract Inhibits Histone De-Acetylase2 Activity in Cervix Cancer Cells in Vitro: Evidence of Epigenetic Modification in Cell Cycle Arrest. J Pharmacopunctue. 2013; 16:7-13.
  19. Bishayee K, Chakraborty D, Ghosh S, Boujedaini N, Khuda-Bukhsh AR. Lycopodine triggers apoptosis by modulating 5-lipoxygenase, and depolarizing mitochondrial membrane potential in androgen sensitive and refractory prostate cancer cells without modulating p53 activity: Signalling cascade and drug-DNA interaction. Eur J Pharmacol. 2013; 698:110–21.
  20. Chakraborty D, Sikdar S, Bishayee K, Mukherjee A, Khuda-Bukhsh AR. Combination of Helonias dioica extract and Metformin improves insulin responsiveness by activating PI3K/AKT pathway signaling in obese hyperglycemic mice. Chinese Journal of Integrative Medicine, Springer, (In Press).
  21. Chakraborty, D, Ghosh, S, Bishayee, K, Mukherjee A, Sikdar S, Khuda-Bukhsh, AR. Anti-hyperglycemic drug Gymnema sylvestre also shows anti-cancer potentials in human melanoma A375 cells via ROS generation and mitochondria-dependent caspase pathway. Integrative Cancer Therapies, 2013;12:433-41. doi: 10.1177/1534735413485419.
  22. Das J, Samadder A, Das S, Paul A, Boujedaini N, Khuda-Bukhsh AR. Potentized homeopathic drug, Phytolacca Decandra 15C, induces apoptosis in lung adenocarcinoma cells A549 through DNA damage and ROS generation. Chinese Journal of Integrated Medicine. (In Press)
  23. Das S, Das J, Paul A, Samadder A, Khuda-Bukhsh AR. Apigenin, a bioactive flavonoid from Lycopodium clavatum, stimulates nucleotide excision repair genes to protect skin keratinocytes from ultraviolet B-induced reactive oxygen species and DNA damage. J Acupunct Meridian Stud. 2013; 6:252-62.
  24. Das S, Das J, Samadder A, Bhattacharyya SS, Das D, Khuda-Bukhsh AR. Biosynthesized silver nanoparticles by ethanolic extracts of Phytolacca decandra, Gelsemium sempervirens, Hydrastis canadensis and Thuja occidentalis induce differential cytotoxicity through G2/M arrest in A375 cells. Colloids Surf B Biointerfaces. 2013; 101: 325-336.
  25. Mukherjee A, Boujedaini N, Khuda-Bukhsh AR. Homeopathic Thuja 30C ameliorates benzo(a)pyrene-induced DNA damage, stress and viability of perfused lung cells of mice in vitro. J Integr Med. 2013;11:397-404. doi: 10.3736/jintegrmed2013054.
  26. Ghosh S, Bishayee K, Khuda-Bukhsh AR. Graveoline isolated from ethanolic extract of Ruta graveolens triggers apoptosis and autophagy in skin melanoma cells: A novel apoptosis-independent autophagic signaling pathway. Phytother Res. 2013 Dec 17. doi: 10.1002/ptr.5107.
  27. Ghosh S, Bishayee K, Paul A, Mukherjee A, Sikdar S, Chakraborty D, Boujedaini N, Khuda-Bukhsh AR. Homeopathic mother tincture of Phytolacca decandra induces apoptosis in skin melanoma cells by activating caspase mediated signaling via Reactive Oxygen Species elevation. J Integr Med. 2013;11:116-24. doi: 10.3736/jintegrmed2013014.
  28. Paul A, Das J, Das S, Samadder A, Khuda-Bukhsh AR. Anticancer potential of myricanone, a major bioactive component of Myrica cerifera: novel signaling cascade for accomplishing apoptosis. J Acupunct Meridian Stud. 2013;6: 188-98.
  29. Paul A, Das J, Das S, Samadder A, Khuda-Bukhsh AR. PLGA nano-encapsulation of chelidonine enhances the ameliorative potential against cadmium induced oxidative damage and hepatic injury in mice. Environ Toxicol Pharmacol.. 2013; 36:937-47.
  30. Paul A, Das S, Das J, Samadder A, Bishayee K, Sadhukhan R, Khuda-Bukhsh AR. Diarylheptanoid-myricanone isolated from ethanolic extract of Myrica cerifera shows anticancer effects on HeLa and PC3 cell lines: signalling pathway and drug-DNA interaction. J Integr Med. 2013;11:405-15.
  31. Paul A, Das S, Das J, Samadder A, Khuda-Bukhsh AR. Cytotoxicity and apoptotic signalling cascade induced by chelidonine-loaded PLGA nanoparticles in HepG2 cells in vitro and bioavailability of nano-chelidonine in mice in vivo. Toxicol Lett. 2013; 222:10-22.
  32. Das S, Das J, Samadder A, Khuda-Bukhsh AR. Dihydroxy-Isosteviol Methyl Ester from Pulsatilla nigricans Induces Apoptosis in HeLa Cells: Its Cytoxicity and Interaction with Calf Thymus DNA. Phytother Res. 2013; 27:664-71. doi: 10.1002/ptr.4768.
  33. Das S, Das J, Samadder A, Paul A, Khuda-Bukhsh Efficacy of PLGA-loaded apigenin nanoparticles in Benzo[a]pyrene and ultraviolet-B induced skin cancer of mice: Mitochondria mediated apoptotic signalling cascades. Food Chem Toxicol. 2013; 62:670-80. doi: 10.1016/j.fct.2013.09.037.
  34. Das S, Das J, Samadder A, Paul A, Khuda-Bukhsh Strategic formulation of apigenin-loaded PLGA nanoparticles for intracellular trafficking, DNA targeting and improved therapeutic effects in skin melanoma in vitro. Toxicol Lett. 2013 Nov 25;223:124-38. doi: 10.1016/j.toxlet.2013.09.012.
  35. Samadder A, Das S, Das J, Paul A, Boujedaini N, Khuda-Bukhsh AR. The potentized homeopathic drug, Lycopodium clavatum (5C and 15C) has anti-cancer effect on HeLa cells in vitro.J Acupunct Meridian Stud. 2013; 6:180-7.
  36. Das S, Saha SK, De A, Das D, Khuda-Bukhsh AR. Potential of the homeopathic remedy, Arnica Montana 30C, to reduce DNA damage in Escherichia coli exposed to ultraviolet irradiation through up-regulation of nucleotide excision repair genes. Jour of Chinese Integrative Medicine 2012; 10:337-46.
  37. Samadder A, Das J, Das S, Khuda-Bukhsh AR. Dihydroxy-isosteviol-methyl-ester, an active biological component of Pulsatilla nigricans, reduces arsenic induced cellular dysfunction in testis of male mice. Environ Toxicol Pharmacol. 2012; 34:743-52. doi: 10.1016/j.etap.2012.09.013.
  38. De A, Das D, Dutta S, Chakraborty D, Boujedaini N, Khuda-Bukhsh A.R. Potentized homeopathic drug Arsenicum Album 30C inhibits intracellular reactive species generation and up-regulates expression of arsenic resistance gene in arsenic exposed bacteria Escherichia Zhong Xi Yi Jie He XueBao. 2012; 10:210-27.
  39. Samadder A, Das J, Das S, De A, Saha SK, Bhattacharyya SS, Khuda-Bukhsh Poly(lactic-co-glycolic) acid loaded nano-insulin has greater potentials of combating arsenic induced hyperglycemia in mice: some novel findings. Toxicol Appl Pharmacol. 2013 ; 15;267:57-73. doi: 10.1016/j.taap.2012.12.018.
  40. Bishayee K, Mukherjee A, Paul A, Khuda-Bukhsh AR. Homeopathic mother tincture of Conium initiates reactive oxygen species mediated DNA damage and makes HeLa cells prone to apoptosis. TANG: International Journal of Genuine Traditional Medicine, 2012, 2: e-26. DOI: 10.5667/tang.2012.0018
  41. Samadder A, Das S, Das J, Paul A, Khuda-Bukhsh AR. Ameliorative effects of Syzygium jambolanum extract and its poly(lactic-co-glycolic) acid nano-encapsulated form on arsenic induced hypoglycemic stress: A multiparametric evaluation. Journal of Acupncture and Meridian Studies, 2012: J Acupunct Meridian Stud. 2012; 5:310-8.
  42. Bhattacharyya SS, Das J, Das S, Samadder A, Das D, De A, Paul S, Khuda-Bukhsh AR. Rapid green synthesis of silver nanoparticles from silver nitrate by a homeopathic mother tincture Phytolacca Decandra. Jour of Chinese Integrative Medicine. 2012; 10:546-54.
  43. Bhattacharjee N, Khuda-Bukhsh AR. Two homeopathic remedies used intermittently provide additional protective effects against hepatotoxicity induced by carcinogens in mice. Journal of Acupuncture and Meridian Studies, 2012; 5:166-75. Doi:10.1016/j.jams.2012.05.004
  44. Das J, Das S, Samadder A, Bhadra K, Khuda-Bukhsh AR. Poly(lactide-co-glycolide) encapsulated extract of Phytolacca decandra demonstrates better intervention against induced lung adenocarcinoma in mice and on A549 cells. Eur J Pharm Sci. 2012 29; 47:313-24. doi: 10.1016/j.ejps.2012.06.018
  45. Samadder A, Das J, Das S, Das D, De A, Bhadra K, Khuda-Bukhsh AR. Dihydroxy-isosteviol methyl ester of Pulsatilla nigricans extract reduces arsenic-induced DNA damage in testis cells of male mice: its toxicity, drug-DNA interaction and signaling cascades.. Jou of Chinese Intgr Medicine, 2012;10:1433-42. doi: 10.3736/jcim20121216.
  46. Paul A, Bishayee K, Ghosh S, Mukherjee A, Sikdar S, Chakraborty D, Boujedaini N, Khuda-Bukhsh AR. Chelidonine isolated from ethanolic extract of Chelidonium majus promotes apoptosis in HeLa cells through p38-p53 and PI3K/AKT signalling pathways. Jour of Chinese Integrative Medicine. 2012; 10:1025-38. Saha SK, Das S, Khuda-Bukhsh AR. Phenotypic evidence of ultra-highly diluted homeopathic remedies to act at gene expression level: a novel probe on experimental phage infectivity in bacteria. Jour of Chinese Integrative Medicine. 2012;10:210-27.
  47. Samadder A, Chakraborty D, De A, Bhattacharyya SS, Bhadra K, Khuda-Bukhsh AR. Possible signaling cascades involved in attenuation of alloxan-induced oxidative stress and hyperglycemia in mice by ethanolic extract of Syzygium jambolanum: drug-DNA interaction with calf thymus DNA as target. Eur J Pharm Sci. 2011; 9;44:207-217. doi: 10.1016/j.ejps.2011.07.012.
  48. Paul S, Bhattacharyya SS, Boujedaini N, Khuda-Bukhsh AR. Anticancer Potentials of Root Extract of Polygala senega and Its PLGA Nanoparticles-Encapsulated Form. Evid Based Complement Alternat Med. 2011; 2011. pii: 517204. doi: 10.1155/2011/517204
  49. Paul S, Bhattacharyya SS, Samaddar A, Boujedaini N, Khuda-Bukhsh AR. Further evidences of anti-cancer potentials of root extract of Polygala senega against benzo[a] pyrene induced lung cancer in mice Jour of Chinese Integrative Med., 2011, 9:320-327.
  50. Khuda-Bukhsh AR, Banerjee A, BiswasSJ, Roy Karmakar S, Banerjee P, Pathak S, Guha B, NaoualB. An initial report on the efficacy of a millesmal potency Arsenicum Album LM 0/3 in ameliorating arsenic toxicity in humans living in a high risk arsenic village. Zhong Xi Yi Jie He Xue Bao. 2011;9:596-604
  51. Bhattacharyya SS, Paul S, De A, Das D. Samadder A, Boujedai N, Khuda-Bukhsh AR. Poly (lactide-co-glycolide) acid nanoencapsulation of a synthetic coumarin: Cytotoxicity and bio-distribution in mice, in cancer cell line and interaction with calf thymus DNA as target. Toxicol Appl Pharmacol. 2011; 253:270-81. doi: 10.1016/j.taap.2011.04.010.
  52. Khuda-Bukhsh AR, Bhattacharyya SS, Paul S, Dutta S, Boujedaini N, Belon P. Modulation of signal proteins: a plausible mechanism to explain how a potentized drug Secale Cor 30C diluted beyond Avogadro’s limit combats skin papilloma in mice. eCAM, 2011; 2011:286320. doi: 10.1093/ecam/nep084
  53. Khuda-Bukhsh AR, De A, Das D, Dutta S, Boujedaini N. Analysis of the capability of ultra-highly diluted glucose to increase glucose uptake in arsenite-stressed bacteria Escherichia coli. Jour of Chinese Integrative Medicine.. 2011; 9: 901-12.
  54. Das D, De A, Dutta S, Biswas R, Boujedaini N, Khuda-Bukhsh AR. Potentized homeopathic drug Arsenicum Album 30C positively modulates protein biomarkers and gene expressions in Saccharomyces cerevisae exposed to arsenate. Jour of Chinese Integrative Medicine. 2011; 9:752-60.
  55. Das D, De A, Khuda-Bukhsh AR. A potentized homeopathic remedy, Arsenicum Album 6C can attenuate Sodium arsenite induced apoptosis in the budding yeast Saccharomyces cerevisiae. AICCG, Bodh Gaya, Nov. 21-23. 2011; 15:55-66.
  56. Biswas R, Mandal SK, Dutta S, Bhattacharyya SS, Boujedani N, Khuda-Bukhsh AR. Thujone rich fraction of Thuja occidentalis demonstrates major anti-cancer potentials: Evidences from in vitro studies on A375 cells. eCAM. 2011; DOI: 10.1093/ecam/neq042.
  57. Banerjee A, Chakrabarty SB, Karmakar SR, Chakrabarty A, Biswas SJ, Haque S, Das D, Paul S, Mandal B, Naoual B, Belon P, Khuda-Bukhsh AR. Can Homeopathy Bring Additional Benefits to Thalassemic Patients on Hydroxyurea Therapy? Encouraging Results of a Preliminary Study. Evidence-Based Complementary and Alternative Medicine. 2010; 7:129-36. doi: 10.1093/ecam/nem161
  58. Banerjee A, Pathak S, Biswas SJ, Roy-Karmakar S, Boujedaini N, Belon P, Khuda-Bukhsh AR. Chelidonium majus 30C and 200C in induced hepato-toxicity in rats. Homeopathy. 2010; 99:167-76. doi: 10.1016/j.homp.2010.05.008.
  59. Bhattacharyya SS, Paul S, Dutta S, Boujedani N, Khuda-Bukhsh AR. Anti-oncogenic potentials of a plant coumarin (7-hydroxy coumarin) against DMBA induced skin papilloma in mice: The possible role of several key signal proteins. Jour of Chinese Integrative Medicine 2010; 8:645-54.
  60. Khuda-Bukhsh AR, Bhattacharyya SS, Paul S, Boujedaini N.Polymeric nanoparticle encapsulation of a naturally occurring plant scopoletin and its effects on human melanoma cell A375. Jour Chinese Intgr Med. 2010; 8:853-62.
  61. Mandal SK, Biswas R, Bhattacharyya SS, Paul S, Dutta S, Pathak S, Khuda-Bukhsh AR. Lycopodine from Lycopodium clavatum extract inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation. Eur J Pharmacol. 2010; 626:115-22.
  62. Bhattacharyya SS, Paul S, Khuda-Bukhsh AR. Encapsulated plant extract (Gelsemium semipervirens) poly (lactide-co-glycolide) nanoparticles enhance cellular uptake and increases bioactivity in vitro. Exp Biol Med (Maywood). 2010; 235:678-88. doi: 10.1258/ebm.2010.009338.
  63. Pathak S, Banerjee A, Khuda-Bukhsh AR. Efficacy of ethanolic spore extract of Lycopodium clavatum in reducing induced hepatotoxicity and genotoxicity in mice. Intl. Jour. of Biol. Chem. Sciences. 2010, 4: 770-781.
  64. Roy Karmakar S, Biswas SJ, Khuda-Bukhsh AR. Anti-carcinogenic potentials of a plant extract (Hydrastis canadensis): I. Evidence from in vivo studies in mice (Mus musculus).Asian Pac J Cancer Prev. 2010; 11:545-51.
  65. Roy Karmakar S, Biswas SJ, Khuda-Bukhsh AR. Anti-carcinogenic potentials of a plant extract (Hydrastis canadensis): I. Evidence from in vivo studies in mice (Mus musculus).Asian Pac J Cancer Prev. 2010; 11:545-51.
  66. Pathak S, Banerjee A, Paul S, Khuda-Bukhsh AR. Protective potentials of a plant extract (lycopodium clavatum) on mice chronically fed hepato-carcinogens. Indian J Exp Biol. 2009:47:602-607.
  67. Bhattacharjee N, Banerjee P, Khuda-Bukhsh AR. Homeopathic drugs Natrum Sulphuricum and carcinosin prevent azo dye-induced hepatocarcinogenesis in mice. Indian J BichemBiophy. 2009; 46:307-18.
  68. Khuda-Bukhsh AR. Mice as a model for homeopathy research. Homeopathy 2009, 98:267-79. doi: 10.1016/j.homp.2009.09.007
  69. Bhattacharjee N, Pathak S, Khuda-Bukhsh AR. Amelioration of Carcinogen Induced Toxicity in Mice by Administration of a Potentized Homeopathic Drug, Natrum Sulphuricum 200. Evid Based Complement Alternat Med. 2009; 6:65-75. doi: 10.1093/ecam/nem067.
  70. Banerjee P, Bhattacharyya SS, Pathak S, Naoual B, Belon P, Khuda-Bukhsh AR. Comparative efficacy of two microdoses of a potentized homeopathic drug, arsenicum album, to ameliorate toxicity induced by repeated sublethal injections of arsenic trioxide in mice. Pathobiology. 2008; 75:156-70.
  71. Khuda-Bukhsh AR, Pathak S. Homeopathic Drug Discovery: Theory update and Methodological aspect. Expert Opinion in Drug Discovery. 2008; 3:979-990.
  72. Biswas SJ, Bhattacharjee N, Khuda-Bukhsh AR. Efficacy of a plant extract (Chelidonium majus L.) in combating induced hepatocarcinogenesis in mice. Food and Chemical Toxicology 2008; 46:1474-87.
  73. Bhattacharyya SS, Mandal SK, Biswas R, Paul S, Pathak S, Boujedaini N, Belon P, Khuda-Bukhsh AR. In vitro studies demonstrate anticancer activity of an alkaloid of the plant Gelsemium sempervirens. ExpBiol Med (Maywood). 2008; 233:1591-601.
  74. Banerjee P, Biswas SJ, Belon P, Khuda-Bukhsh AR. A potentized homeopathic drug, Arsenicum Album 200, can ameliorate genotoxicity induced by repeated injections of arsenic trioxide in mice. J Vet Med A Physiol Pathol Clin Med. 2007; 54:370-6.
  75. Belon P, Banerjee A, Karmakar SR, Biswas SJ, Choudhury SC, Banerjee P, Das JK, Pathak S, Guha B, Paul S, Bhattacharjee N, Khuda-Bukhsh AR. Homeopathic remedy for arsenic toxicity?: Evidence-based findings from a randomized placebo-controlled double blind human trial. Sci Total Environ. 2007; 384:141-50.
  76. Pathak S, Bhattacharjee N,Das JK, Choudhury SC, Roy-Karmakar S , Banerjee P, Paul S, Banerjee A, Khuda-Bukhsh AR. Supportive evidences for anti-cancerous potential of an alternative medicine in hepatocarcinogenesis of mice, Research in Complementary Medicine (Forsch Komplementarmed). 2007; 14:148-156.
  77. Pathak S, Das JK, Biswas SJ, Khuda-Bukhsh AR. Protective potentials of a potentized homeopathic drug, Lycopodium-30, in ameliorating azo dye induced hepatocarcinogenesis in mice. Mol Cell Biochem. 2006; 285:121-31.
  78. Belon P, Banerjee P, Choudhury SC, Banerjee A, Biswas SJ, Karmakar SR, Pathak S, Guha B, Chatterjee S, Bhattacharjee N, Das JK, Khuda-Bukhsh Can administration of potentized homeopathic remedy, Arsenicum album, alter antinuclear antibody (ANA) titer in people living in high-risk arsenic contaminated areas? I. A correlation with certain hematological parameters. Evid Based Complement Alternat Med. 2006; 3:99-107.
  79. Khuda-Bukhsh A.R. Laboratory Research in homeopathy: pro. Integrative Cancer Therapies. 2006; 5: 320-32.
  80. Khuda-Bukhsh AR, Pathak S, Guha B, Karmakar SR, Das JK, Banerjee P, Biswas SJ, Mukherjee P, Bhattacharjee N, Choudhury SC, Banerjee A, Bhadra S, Mallick P, Chakrabarti J, Mandal B. Can homeopathic arsenic remedy combat arsenic poisoning in humans exposed to groundwater arsenic contamination?: a preliminary report on first human trial. Evid Based Complement Alternat Med. 2005; 537-48.
  81. Biswas SJ, Pathak S, Bhattacharjee N, Das JK, Khuda-Bukhsh AR. Efficacy of a potentized homeopathic drug, Carcinosin-200, fed alone and in combination with another drug, Chelidonium 200, in amelioration of p-DAB induced hepatocarcinogenesis in mice. Altern.  Comp Med. Mary Ann Liebert Pub 2005; 11:839-854.
  82. Datta S, Biswas SJ, Khuda-Bukhsh AR. Comparative Efficacy of Pre-feeding, Post-feeding and Combined Pre- and Post-feeding of Two Microdoses of a Potentized Homeopathic Drug, MercuriusSolubilis, in Ameliorating Genotoxic Effects Produced by Mercuric Chloride in Mice. Evid Based Complement Alternat Med 2004: 1:291-300.
  83. Biswas SJ, Khuda-Bukhsh Evaluation of protective potentials of a potentized homeopathic drug, Chelidonium majus, during azo dye induced hepatocarcinogenesis in mice. Indian J Exp Biol. 2004; 42:698-714.
  84. Khuda-Bukhsh Towards understanding molecular mechanisms of action of homeopathic drugs: an overview. Mol Cell Biochem. 2003; 253:339-45.
  85. Mallick P, Mallick JC, Guha B, Khuda-Bukhsh AR. Ameliorating effect of microdoses of a potentized homeopathic drug, Arsenicum Album, on arsenic-induced toxicity in mice. BMC Complement Altern Med. 2003; 22:3-7.
  86. Biswas SJ, Khuda-Bukhsh A.R. Effect of a homeopathic drug, Chelidonium, in amelioration of p-DAB induced hepatocarcinogenesis in mice. BMC Complementary & Alternative Medicines. 2002; 2:1-16.
  87. Chakrabarti J, Biswas SJ, Khuda-Bukhsh AR. Cytogenetical effects of sonication in mice and their modulations by actinomycin D and a homeopathic dug., Arnica 30. Indian J Exp Biol. 2001;39:1235-42.
  88. Datta S, Mallick P, Khuda-Bukhsh AR. Comparative efficacy of two microdoses of a potentized homoeopathic drug, Cadmium Sulphoricum, in reducing genotoxic effects produced by cadmium chloride in mice: A time course study. BMC Complementary and Alternative Med. 2001; 1:1-18.
  89. Khuda-Bukhsh AR. The efficacy of potentized homeopathic drug in combating arsenic poisioning: A suggestive scientific probe. in Cytol. & Genet. 2001; 10:231-239.
  90. Kundu SN, Mitra K, Khuda-Bukhsh AR. Efficacy of a potentized homoeopathic drug (Arsenicum Album-30) in reducing cytotoxic effects produced by of arsenic trioxide in mice. III. Tissue damage recovery, and enzymatic changes in liver. Comp Ther Med. 2000; 8:76-81.
  91. Kundu SN, Mitra K, Khuda-Bukhsh AR. Efficacy of a potentized homoeopathic drug (Arsenicum Album-30) in reducing cytotoxic effects produced by of arsenic trioxide in mice. IV. On certain pathological conditions, gel electrophoretic protein profiles, DNA and RNA. Comp Ther Med. 2000;8:157-65.
  92. Datta S, Mallick P, Khuda-BukhshEfficacy of a potentized homeopathic drug (Arsenicum Album -30) in reducing genotoxic effects produced by arsenic trioxide in mice: comparative studies of pre-, post-, pre- and post-oral administration and comparative efficacy of two microdoses. Com Ther Med. 1999; 7:62-75.
  93. Mitra K, Kundu SN, Khuda-Bukhsh AR. Efficacy of a potentized homoeopathic drug (Arsenicum Album-30) in reducing cytotoxic effects produced by of arsenic trioxide in mice.II. On alterations in body weight, tissue weight and total protein. CompTher Med. 1999;7:24-34
  94. Datta S , Khuda-Bukhsh AR. Efficacy of a potentized homeopathic drug, Stannum 30, in modifying clastogenic effects of Stannum chloride in mice. Perspecives in Cytol. & Genet. 1998; 9:345-51.
  95. Mitra K, Kundu SN, Khuda-Bukhsh AR. Efficacy of a potentized homoeopathic drug (Arsenicum Album-30) in reducing cytotoxic effects produced by of arsenic trioxide in mice. I. On rate of accumulation of arsenic in certain vital organs. Comp Ther Med. 1998:6:178-184.
  96. Khuda-Bukhsh AR. Potentized homeopathic drugs act through regulation of gene expression: A hypothesis to explain their mechanism and pathways of action in vivo. Comp Ther Med. 1997; 5:43-6.
  97. Banik S, Khuda-Bukhsh AR. Alterations of cytogenetical and haematological effects by ultra-low doses of Ginseng in whole-body X-irradiated mice. Nucleus. 1996; 49:28-35
  98. Khuda-Bukhsh AR. Alteration of X-ray effects by homeopathic drugs: a new approach in radio-protection. In: Manna GK, Roy SC, eds. Perspectives in Cytology and Genetics, Vol.8. Calcutta: All India Congress of Cytology and Genetics, 1995: pp 649-663.
  99. Banik S, Khuda-Bukhsh AR. Quantitative assessment of spermhead anomaly in X-irradiated mice and the alteration of frequency by the oral administration of a potentized homeopathic drug, Ginseng. Proc. Sym. “Zoological Research in Relation to Man and Environment”, Calcutta University, 1-4 March, 1992, In: Proc. Zool. Soc., Calcutta, 1992:45:243-248.
  100. Khuda-Bukhsh AR, Banik S. Assessment of cytogenetical damages in X-irradiated mice and their alterations by oral administrations of a potentized homeopathic drug, Ginseng 200. Berlin J Res Hom. 1991; 1:254-63.
  101. Khuda-Bukhsh AR, Maity S. Alterations of cytogenetic effects by oral administration of a homeopathic drug, Ruta Graveolens, in mice exposed to sub-lethal X-irradiation. Berlin J Res Hom. 1990; 1:264-274.
  102. Khuda-Bukhsh AR. Some homeopathic drugs as radio-protective agents in X-irradiated mice. In: In Cytol. Genet, Eds. G.K. Manna and U. Sinha. 1986; 5:407-12.
  103. Khuda-Bukhsh AR, Goswami S, Barat A, Sadhukhan G, Mukherjee A. X-ray induced chromosomal aberrations and their alterations by the oral administration of a homeopathic drug, Arnica Montanma, in mice. Proc. Sem on. the “Effects of Environmental Agents on Genetical Systems”, Calcutta University, 18-20 Oct., 1982, pp. 2-3.

Professor Anisur Rahman Khuda-BukhshProfessor Anisur Rahman Khuda-Bukhsh,
Prof. A.R. Khuda-Bukhsh,, Ph.D.
Emeritus Professor, UGC, Govt. of India,
at University of Kalyani, Kalyani-741235, W.B.
E–mail: prof_arkb@yahoo.co.in  or khudabukhsh_48@rediffmail.com

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