Sweet sugar pills for bitter menstrual migraines

Bishnoi Anju1,Bishnoi Suresh2

Abstract:  Migraine comprises a composite collection of symptoms, disturbing the nervous system, the gastro-intestinal tract and the vascular system. More than “just a headache” it is a disorder of central nervous system dysregulation. Migraine is three times more common in women than in men and is the 4th leading cause of disability in women. Onset of migraine increases at menarche, with peaks in prevalence in the late 30s, and a rapid decline after menopause.

Keywords: Menstrual migraine, Hormonal factors, Homoeopathy.

Introduction-

Migraine is a complex central nervous system disorder which is primarily characterized by headaches of long duration, with moderate to severe pain and associated symptoms such as light and sound sensitivity (photo- and phono phobia), nausea and vomiting [1]. Abundant population data suggest that hormonal factors may trigger headache attacks and influence onset and remission. Drops in estrogen presumably lead to increased migraine attacks at the time of menses as well as during the menopausal transition.[2]

Incidence and prevalence of menstrual migraine – Four of every ten women and two of every ten men will contract migraine in their lifetime, most before age 35 years. More than 50% of women with migraine, both in the general population and presenting to specialist clinics, report an association between migraine and menstruation.[3]

The peak incidence of migraine during the menstrual cycle occurs on the days directly before and after the first day of menstruation.[4]

Migraine subtypes– The two primary types of migraine are migraine without aura which accounts for the majority of cases (approximately 80%) and migraine with aura which accounts for about 20%. [1,5]

Migraine without aura:  Is a clinical syndrome characterized by headache with specific features and associated symptoms. It is also known as common migraine or Hemicrania simplex.

Migraine with aura:  It is primarily characterized by the transient focal neurological symptoms that usually precede or sometimes accompany the headache. It is also called Classical migraine or Complicated migraine. [6]

Of the two, migraine without aura is the type primarily associated with hormonal fluctuations, and thus is the primary focus of this review.[7,8] Among women, migraine can be further subdivided with respect to its relationship to menstruation (Table) [1,7]

Table -Diagnostic criteria for Menstrual Migraine

International Headache Society (ICHD-3beta) (Headache Classification, 2013)
Diagnostic Criteria

Pure menstrual migraine Documented and prospectively collected evidence that attacks occur exclusively on day 1 ± 2 (i.e., days −2 to + 3)a of menstruation in at least two out of three menstrual cycles and at no other times of the cycle
Menstrually-related migraine Documented and prospectively collected evidence that attacks occur on day 1 ± 2 (i.e., days −2 to + 3)a of menstruation in at least two out of three menstrual cycles and additionally at other times of the cycle
Non-menstrual migraine Attacks have no menstrual relationship

aThe first day of menstruation is day 1 and the preceding day is day − 1; there is no day 0

Diagnostic Criteria for Migraine: Repeated attacks of headache lasting 4–72 h in patients with a normal physical examination, no other reasonable cause for the headache, and: At least 2 of the following features: Unilateral pain, Throbbing pain, Aggravation by movement, Moderate or severe intensity. At least 1 of the following features: Nausea/vomiting, Photophobia and phonophobia[9]

Representation of menstrual migraine in Repertories: [10,11,12,13,14]

  • BOERICKE’S REPERTORY

HEAD, Headache (cephalalgia), Type, menstrual.

  • KENT REPERTORY

HEAD, Pain, Menses , Commencement of, at-

  • BOGER BOENNINGHAUSEN’S CHARACTERISTICS AND REPERTORY

HEAD – Internal – aggravation;menses after

  • PHATAK CONCISE REPERTORY

HEAD: menses; before and after agg.

  • MURPHY REPERTORY

HEADACHE-migraine- menses,before

Homoeopathic Approach[10,15,16,17]

  • Avena sativa – Nervous headache at menstrual period with burning at top of head. Occipital headache with phosphatic urine. Nervous states of many female troubles.
  • Joanesa asoca– Unilateral headache ,reflex uterine, congestive headache better open air and by free flow.
  • Laurocerasus– Menses too frequent ,profuse, thin with tearing in vertex at night. Want of animal heat and reaction. Feeble circulation and weak heart.
  • Allium sativum– Heavy; pulsation in temples; catarrhal deafness. Has vasodilatory properties. headache before menses, ceases during agg. afterwards.
  • Glycerinum– Head full throbs, mentally confused. Severe headache two days before menstruation.
  • Ustilago maydis– Full feeling, nervous headache from menstrual irregularities.
  • Xanthoxyllum fraxineum – A tightening of scalp and heavy pain in temples, increase of head difficulties with great heat and quite flowing (menstrual),being two days in advance of proper time;
  • Chionanthus– Often service in many types of headache, neurasthenic, periodical sick headache, menstrual and bilious.
  • Lac vaccinum defloratum– Intense throbbing with nausea, vomiting, blindness and obstinate constipation; worse noise, light, motion, during menses with great prostration, better by pressure and bandaging head tightly.

REFERENCES-

  1. The International Classification of Headache Disorders, 3rd edition .Headache Classification Committee of the International Headache Society (IHS).Cephalalgia. 2013 Jul; 33(9):629-808.
  2. Pavlović JM. The impact of midlife on migraine in women: summary of current views. Womens Midlife Health. 2020 Oct 6;6:11. doi: 10.1186/s40695-020-00059-8. PMID: 33042563; PMCID: PMC7542111
  3. MacGregor EA, Brandes J, Eikermann A, Giammarco R .Impact of migraine on patients and their families: the Migraine And Zolmitriptan Evaluation (MAZE) survey-Phase III. Curr Med Res Opin.2004 Jul; 20(7):1143-50.
  4. MacGregor EA, Hackshaw A Neurology .Prevalence of migraine on each day of the natural menstrual cycle.2004 Jul 27; 63(2):351-3.
  5. Russell MB, Rasmussen BK, Thorvaldsen P, Olesen J. Prevalence and sex-ratio of the subtypes of migraine. Int J Epidemiol. 1995;24(3):612–8. [PubMed].
  6. Charles A. The Evolution of a Migraine Attack .A Review of Recent Evidence. Headache: The Journal of Head and Face Pain.:2012.
  7. MacGregor EA. Classification of perimenstrual headache: clinical relevance. Curr Pain Headache Rep.2012;16(5):452–60. [PubMed]
  8. Loder EW. Menstrual migraine: pathophysiology, diagnosis, and impact. Headache. 2006;46 (Suppl 2):S55–60. [PubMed].
  9. Longo LD, Fauci SA, Kasper LD, Hoser LS, Jameson LJ, Loscalzo J. Harrison’s manual of medicine. 21th Mc Graw Hill Medical. New York:55;308.
  10. Boerrike W. Pocket Manual of Homoeopathic Materia Medica and Repertory.9thNew Delhi:B Jain Publishers (P) Ltd; 2010.
  11. Kent JT. Repertory of Homoeopathic Materia Medica. 6thNew Delhi:B Jain Publishers (P) Ltd; 2007.
  12. Boger C M. Boger Boenninghausen’s Characteristics and Repertory.New Delhi: B Jain publishers (P)Ltd; 2002.
  13. Phatak SR. Concise Repertory of Homoeopathic Medicines.2nd New Delhi: B Jain publishers (P)Ltd; 1992.
  14. Murphy R. Homeopathic Medical Repertory: A Modern Alphabetical Repertory.3rdNew Delhi: B Jain publishers (P)Ltd; 2014.
  15. Kent JT. Lectures on Homœopathic Materia Medica. 1stNew Delhi: B Jain publishers (P)Ltd; 2002.
  16. Phatak SR. Materia Medica of Homoeopathic Medicines.1st revised ed. New Delhi: B Jain publishers (P)Ltd;
  17. Clarke JH. A Dictionary of Practical Material Medica..3rd New Delhi:B Jain (P)Ltd;vol 3,2005.

Anju Bishnoi (BHMS,MD)
PhD (persuing) Tantia University, SriGanganagar(Raj.)
Email:anjubishnoi129@gmail.com

Suresh Bishnoi (BHMS)
Homoeopathic Consultant, Jaipur (Raj.)
Email:Sureshv292929@gmail.com

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