{"id":55847,"date":"2022-07-05T03:22:49","date_gmt":"2022-07-05T03:22:49","guid":{"rendered":"https:\/\/www.homeobook.com\/?p=55847"},"modified":"2022-07-05T03:22:49","modified_gmt":"2022-07-05T03:22:49","slug":"syzygium-cumini-in-the-treatment-of-polycystic-ovarian-syndrome","status":"publish","type":"post","link":"https:\/\/www.homeobook.com\/syzygium-cumini-in-the-treatment-of-polycystic-ovarian-syndrome\/","title":{"rendered":"Syzygium cumini in the treatment of polycystic ovarian syndrome"},"content":{"rendered":"

Dr Lakshmipriya B Menon<\/strong><\/p>\n

ABSTRACT
\n<\/strong>Polycystic Ovarian Syndrome is commonly affecting as many as 1 out of 15 women. In modern system, the line of management is usually by HRT (hormone replacement therapy) or surgery. Community based studies using Rotterdam criteria among the reproductive age group women have demonstrated varied prevalence features in Asian countries ranging from 2% to 7.5%.<\/p>\n

KEYWORDS : Polycystic ovarian syndrome, Syzygium cumini<\/p>\n

INTRODUCTION<\/p>\n

PCOS,<\/strong> increased during the reproductive age as an endocrine disorder which affects one in each 15 women worldwide. The prevalence rate of obesity is high among the female with PCOS.<\/p>\n

Polycystic ovary syndrome was known before as Stein-Leventhal syndrome<\/strong>. The disorder is related to series of disturbances in the hypothalamic \u2013pituitary \u2013ovarian axis <\/strong>and with androgen \u2013creating tumors to difficulty of getting pregnancy.<\/p>\n

The disease occurs during the reproductive age as increases among the adolescent females and the young women and may be occur at birth but does not cause symptoms until puberty 1<\/sup><\/strong><\/p>\n

There are many causes of irregular periods but PCOS is the most common cause. About 7% of the overall population, about 25% of young fertile women and over 50% of women with irregular periods have PCOS. If you have menstrual periods less frequently than every 35 days or more than 5 weeks between periods, you very well may have PCOS. Over 90% of women with PCOS also have some clinical evidence of androgen excess, including excess hair growth above their upper lip, chin, breasts, or abdomen, or acne. Most of these symptoms will start in the teen years. Certain ethnic groups with overall fewer body hair follicles don\u2019t exhibit this, e.g., women of Asian descent. Specific blood tests can help identify elevated male hormones (androgens) in women.<\/p>\n

Many women with PCOS have some degree of insulin resistance, that is, elevated insulin with normal glucose levels, prediabetes or true diabetes.2<\/sup><\/strong><\/p>\n

What causes PCOD:<\/strong><\/p>\n

Raised levels of Testosterone<\/strong> \u2013 Androgens or “male hormones,” although all women make small amounts of androgens…Higher than normal androgen levels in women can prevent the ovaries from releasing an egg (ovulation) during each menstrual cycle. Excess androgen produced by the theca cells of the ovaries, due either to hyperinsulinemia or increased luteinizing hormone (LH) levels.<\/p>\n

Raised levels of Luteinizing Hormone (LH) <\/strong>\u2013 Due to increased production from the anterior pituitary. This stimulates ovulation but may have an abnormal effect on the ovaries if levels are too high.<\/p>\n

Low levels of Sex Hormone-Binding Globulin (SHBG<\/strong>) \u2013 A protein in the blood, which binds to testosterone and reduces the effect of testosterone.<\/p>\n

Raised levels of Prolactin<\/strong> – Hormone that stimulates the breast glands to produce milk during pregnancy.<\/p>\n

High levels of Insulin (a hormone that helps convert sugars and starches into energy) If you have insulin resistance, your ability to use insulin effectively is impaired, and also your pancreas has to secrete more insulin to make glucose available to cells (so, hyperinsulinaemia) Excess insulin might also affect the ovaries by increasing androgen production, which may interfere with the ovaries’ ability to ovulate 3<\/sup><\/strong><\/p>\n

Signs and symptoms:<\/strong><\/p>\n