{"id":57901,"date":"2024-02-16T04:19:31","date_gmt":"2024-02-16T04:19:31","guid":{"rendered":"https:\/\/www.homeobook.com\/?p=57901"},"modified":"2024-02-16T04:19:31","modified_gmt":"2024-02-16T04:19:31","slug":"an-overview-on-acne-vulgaris-and-homoeopathic-treatment","status":"publish","type":"post","link":"https:\/\/www.homeobook.com\/an-overview-on-acne-vulgaris-and-homoeopathic-treatment\/","title":{"rendered":"An overview on acne vulgaris and homoeopathic treatment"},"content":{"rendered":"

Dr Sangeeta PG scholar<\/strong><\/p>\n

ABSTRACT
\n<\/strong>Acne is a common multifactorial inflammatory condition affecting most commonly adolescent population and disturbing person’s Quality of life(QOL). Many internal and external factors play a role in development of acne. Homeopathic medicine given on the holistic approach and standard principles will give the absolute relieve leaving no scars.<\/p>\n

KEY WORDS: Acne vulgaris, Homoeopathy, Quality of life.<\/p>\n

INTRODUCTION
\n<\/strong>Acne is a common multifactorial chronic inflammation of the pilosebaceous units. The condition is extremely common; it generally starts after puberty and there are reports of it affecting over 90% of adolescents. It is usually most severe in the late teenage years but can persist into the thirties and forties, particularly in females.1<\/sup><\/p>\n

Acne is estimated to affect 9.4% of the global population, making it the 8th<\/sup> most prevalent disease worldwide.2<\/sup><\/p>\n

inflammatory disease of the pilosebaceous unit resulting from androgen-induced increased sebum production, altered keratinisation, inflammation, and bacterial colonisation of hair follicles on the face, neck, chest, and back by Propionibacterium acnes.3<\/sup><\/p>\n

It affects 80% of the population in the age group of 11 to 30 years.4<\/sup><\/p>\n

AETIOLOGY<\/strong>1
\n<\/sup>The key components are increased sebum production; colonisation of pilosebaceous ducts by Propionibacterium acnes, which in turn causes inflammation; and hypercornification and occlusion of pilosebaceous ducts. Severity of acne is associated with sebum excretion rate, which increases at puberty. Both androgens and progestogens increase sebum excretion. There may be a positive family history; there is high concordance in monozygotic twins.<\/p>\n

PATHOGENESIS4
\n<\/sup><\/strong>Acne results from a complex interplay of increased sebum production, ductal hypercornification, follicular colonisation with Propionibacterium acnes, and inflammation. Acne lesions begin with the microcomedo, a microscopic lesion not visible to the naked eye. With time, the follicle fills with lipids, bacteria and cell fragments. Ultimately, a clinically apparent lesion occurs, either a non-inflammatory lesion (open or closed comedo) or an inflammatory lesion.<\/p>\n

Comedogenesis is unique to acne and ductal hypercornification is a key step in it. There is hyper proliferation and abnormal cellular differentiation in the follicular infundibulum, resulting in accumulation of excess and sticky keratinocytes that turn into plugs (comedones). Propionibacterium acnes, a Gram-positive, rod-like bacterium, resides in sebaceous follicles and contributes to comedogenesis and inflammation in acne through production of lipases and proteases, through elaboration of cytokines (TNF-\u03b1, IL-1\u03b1, IL-8), and through activation of toll-like receptor 2.<\/p>\n

\u00a0<\/strong>CLINICAL FEATURES<\/strong><\/p>\n